Charcot-Marie-Tooth Disease

Charcot-Marie-Tooth disease, or CMT is the most common inherited disorder of the peripheral nervous system, affecting approximately 1 in 2,500 individuals. CMT, also known as hereditary motor and sensory neuropathy (HMSN) or peroneal muscular atrophy, comprises a group of disorders that affect peripheral nerves. The peripheral nerves lie outside the brain and spinal cord and supply the muscles and sensory organs in the limbs. Disorders that affect the peripheral nerves are called peripheral neuropathies. Genetic and prenatal tests are available.